Download PDF by Hanan Frenk: A Critique of Nicotine Addiction (Neurobiological Foundation

By Hanan Frenk

ISBN-10: 0306472325

ISBN-13: 9780306472329

ISBN-10: 0792372255

ISBN-13: 9780792372257

Nicotine is nearly universally believed to be the key issue that motivates smoking and impedes cessation. experts equivalent to the general practitioner basic of america and the Royal collage of Physicians within the united kingdom have declared that nicotine is as addictive as heroin and cocaine. This publication is a critique of the nicotine habit speculation, in line with a severe overview of the study literature that purports to end up that nicotine is as addictive drug. The assessment relies on a re-evaluation of greater than seven hundred articles and books in this topic, together with animal and human experimental stories, results of `nicotine substitute therapies', and plenty of different proper assets. This overview concludes that on current proof, there's each cause to reject the commonly accredited conception that nicotine has an immense function in cigarette smoking. A severe exam of the standards for drug habit demonstrates that none of those standards is met via nicotine, and that it's more likely that nicotine in reality limits particularly than allows smoking.

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Reinforcements in the studies we shall discuss are typically delivered in a fixed ratio of bar presses. If they are delivered every time the animal presses the bar, the ratio is referred to as ‘Fixed Ratio 1 (FR1);’ if at every other time, ‘Fixed Ratio 2 (FR2),’ etc. 1 Drugs as Positive Operant Reinforcers: The Self-Administration Paradigm The positive reinforcing value of drugs for animals can be tested, in principle, by reversing the logic of operant reinforcement procedures. When a scientist trains a rat to press the lever for food, he or she has a priori knowledge that food is rewarding to rats.

The wine connoisseur makes fine discriminations between different wines, and has preferences for very specific ones. He or she might settle at times for a basic table wine with dinner, but in the absence of wine would not resort to medicinal alcohol. It would be preposterous to argue that for such a person, wine is just a means of delivering alcohol to the bloodstream. This also holds for tea and coffee. While some people use coffee as a stimulant, for many others the psychoactive agent in the beverage may actually interfere with its consumption, as the success of decaffeinated coffee and tea testifies.

2 Patterns of Substance Use As we suspect some readers may know, “La Route des Vins” (the road of the wines) is not a street in Paris. It appears in the 1995 Michelin Guide de Tourisme499 of the Upper Rhine (“Rhin Superieur, p. 143”), instructing wine aficionados how to reach the wine producers of the area. It is not unique: the route of the “Vignoble et Eaux-vives498” is another prime example of places where wine-lovers to whom the “use of a psychoactive drug (or drugs) takes on high priority” and who are preoccupied “with a desire to obtain and take” these drugs can indulge in “persistent drug-seeking behavior,” thus fulfilling all of the “necessary descriptive characteristics” of the 1993 WHO definition of drug dependence.

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A Critique of Nicotine Addiction (Neurobiological Foundation of Aberrant Behaviors) by Hanan Frenk


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