Aging: Theories and Potential Therapies - download pdf or read online

By Joseph Panno

ISBN-10: 0816049513

ISBN-13: 9780816049516

There are nearly as many theories in regards to the getting older approach as there are researchers operating within the box. This stems from the truth that scientists don't know why animals become old and view each point of an animal's body structure, biochemistry, and molecular biology in trying to resolution this crucial query. the present development between biologists learning the way in which animals get older is to maintain the theories in brain, yet to concentration their consciousness on dominant age-related ailments equivalent to Alzheimer's or heart problems. This new quantity within the New Biology set tackles the interesting topic of getting older, from average procedures to technological advancements, and descibes previous and current study into extending the human lifestyles span. diversified theories approximately getting older and the experiences of the fruit fly and housefly, that have supplied a foundation of information during this box, are offered in a transparent and concise demeanour. using hormone treatment is explored as a potential solution to opposite the results of getting older, using antioxidants is mentioned as one other quarter being pursued by means of scientists trying to locate the major to extending the human existence span, and attainable uncomfortable side effects and financial bills also are tested. Concluding with a suite of biographies of influential researchers during this box, a bibliography, a word list, and an index, getting older offers the complete tale in regards to the hopes, efforts, growth, and realities of this undying subject.

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Extra resources for Aging: Theories and Potential Therapies

Sample text

One might wonder why the body bothers with such an indirect mechanism: Why not let each cell take up glucose whenever it can? The 36 Aging short answer to this question is that each cell would take up the glucose—a process that requires energy—whether it needed it or not. Dependence on insulin makes it possible for the endocrine system to regulate the uptake of glucose. For example, if the animal has a meal, but each cell already has plenty of ATP on hand, the endocrine system blocks the uptake of glucose everywhere but the liver, which is instructed to convert the glucose into glycogen, a molecule that serves as a storage depot.

Labeled mRNA is hybridized to the array to determine which genes are active (white spots) and which are not (gray spots). This simulated array shows the expression of 100 genes. providing the information necessary for a fresh start. Scientists will soon be able to determine the behavior of all 30,000 human genes, in every organ and tissue of the body, throughout the human life span. The effort has already begun. Scientists at the University of Wisconsin have recently reported the results of a study in which they evaluated the activity of 20,000 genes in cells from the prostate gland, before and after the cells attained replicative senescence.

The study consisted of two groups, one receiving a combination of estrogen and progesterone, the other a placebo. The results showed an increased risk in the group receiving hormone therapy for breast cancer, heart attacks, and stroke. However, the effect was relatively small. For example, the study suggested that of 10,000 women getting hormone therapy for a year, eight more will develop invasive breast cancer and seven more will have heart attacks compared with a similar group not taking hormones.

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Aging: Theories and Potential Therapies by Joseph Panno


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